In 1985, East Indian disease specialist Abraham Verghese settles in Johnson City, TN, where his compassion and nonjudgmental treatment brings a sense of comfort to those living with AIDS.

Naveen Andrews
as Dr. Abraham Verghese

Glenne Headly
as Vickie Talley

Hal Holbrook
as Lloyd Flanders

Swoosie Kurtz
as Hope Flanders

Marisa Tomei
as Mattie Vines

Adam Tomei
as Gordon Vines

Ellora Patnaik
as Rajani Verghese

Peter MacNeill
as Allen

Michael Harris
as Trevor

Sean Hewitt
as Chester Mews