A young woman is forced to return to the conservative small town where her bizarre family lives to take care of her mother, having to deal with the cruel reality of her mom's Alzheimer disease and become the daughter they need.

Julia Louis-Dreyfus
as Midge Leavitt (voice)

Abbi Jacobson
as Sarah Leavitt (voice)

Bryan Cranston
as Rob Leavitt (voice)

Samira Wiley
as Donimo (voice)

Beanie Feldstein
as Hannah Leavitt (voice)

Seth Rogen
as Zach (voice)

Wanda Sykes
as Paula (voice)

Bowen Yang
as Dale (voice)

Pamela Adlon
as Debbie (voice)

Sarah Silverman
as Sukey (voice)