When Alzheimer's disease begins to strip away her mother's vibrant personality, a headstrong young woman is forced to return to her oddball family in the conservative small town she recently fled in order to care for her. She quickly realizes she must accept the cruel and warped reality of the disease, and the imperfect beauty of her family, in order to become the daughter they need.

Julia Louis-Dreyfus
as Midge (voice)

Abbi Jacobson
as Sarah (voice)

Bryan Cranston
as Rob (voice)

Samira Wiley
as Donimo (voice)

Beanie Feldstein
as Hannah (voice)

Seth Rogen
as Zach (voice)

Wanda Sykes
as Paula (voice)

Bowen Yang
as Dale (voice)

Pamela Adlon
as Debbie (voice)

Sarah Silverman
as Sukey (voice)