Amidst the outbreak of the 1910 Manchurian Plague, a young Chinese doctor must defy prejudices of both the East and the West to champion his groundbreaking theory about the disease's deadly evolution.

Chris Pang
as Dr. Wu Lien-teh

Jim Lau
as Master Yao Shi-jie

Michael Monasterio
as Dr. Gerald Mesny

Albert Kuo
as Lim Chia-Swee

Kevin O’Sullivan
as Russian Soldier