Giuseppe Moscati, Doctor saint of Naples, was a doctor of the early twentieth century, from an aristocratic family devoted his career to serving the poor. The film focuses on the human side, partially leaving aside the spiritual part.

Giuseppe Fiorello
as Giuseppe Moscati

Kasia Smutniak
as Elena Cajafa

Ettore Bassi
as Giorgio Piromallo

Carmine Borrino
as Umberto

Paola Casella
as Cloe

Giorgio Colangeli
as De Lillo

Marco Gambino
as Fascist

Emanuela Grimalda
as Suor Helga

Paolo Casiraghi
as Gregario

Giuseppe Zeno
as Arcangelo