Following an argument with his young protege, the curmudgeonly Dr. Gillespie dumps Jimmy Kildare in a street clinic, hoping to teach him a lesson. While working there Kildare meets pretty nurse Mary Lamont, and ends up treating a hoodlum with a gunshot wound. He purposely fails to write a report on it, and soon finds himself in a heap of trouble. Who else would come to his rescue but good old Dr. Gillespie?

Lew Ayres
as Dr. James Kildare

Lionel Barrymore
as Dr. Leonard Gillespie

Laraine Day
as Nurse Mary Lamont

Nat Pendleton
as Joe Wayman

Lana Turner
as Rosalie Lewett

Samuel S. Hinds
as Dr. Stephen Kildare

Lynne Carver
as Alice Raymond

Emma Dunn
as Mrs. Martha Kildare

Walter Kingsford
as Dr. Walter Carew

Alma Kruger
as Molly Byrd