After her ex-convict husband Bill is killed in a bank robbery, Nancy Preston and her young son Bubsy are protected by Mike Horgan, a former friend from Sing Sing. Mike is wrongfully jailed, and Nancy—falsely accused of murdering a criminal fence who tried to abuse her—goes on the run. Mike breaks out of prison to join Nancy in a small town where he practices medicine under his real name, Stafford. When a persistent detective tracks them down, he falls ill, gets nursed back to health by the pair, has a change of heart, and proves Nancy's innocence so she and Mike can marry.

Marguerite De La Motte
as Nancy Preston

John Bowers
as Mike Horgan

Frankie Darro
as Bubsy

David Butler
as Bill Preston

William V. Mong
as Pasquale

Alphonse Ethier
as Tierney

Edgar Kennedy
as Gloomy Gus

Gertrude Short
as Agnes

Ray Gallagher
as Texas Darcy

Jackie Saunders
as Hazy Mazie