Fifty years ago, mysterious creatures known as the "Huge" suddenly appeared all over the world, posing an existential threat to humanity. To defend against these menaces, soldiers in the form of teenage girls known as "Lilies" use the energy of magie within their bodies to power weapons called "Counter Huge ARMS", or CHARMs. After being saved by a Lily two years ago while evacuating from a Huge attack, Hitotsuyanagi Riri vowed to become a Lily herself. She enrolls in the prestigious academy of Yurigaoka, a training ground for Lilies, in order to be reunited with Shirai Yuyu — the Lily who rescued her. Much to her confusion, however, the person she thought to be cheerful turns out to be quite antisocial and prefers to fight alone. Even so, Riri still wants to get close to Yuyu and is willing to do anything she can to reach that goal.

Hikaru Akao
as Hitotsuyanagi Riri

Yuko Natsuyoshi
as Shirai Yuyu

Mikako Izawa
as Kaede Johan Nouvel

Rimi Nishimoto
as Futagawa Fumi

Risa Tsumugi
as Ando Tazusa

Haruki Iwata
as Yoshimura Thi Mai

Sana Hoshimori
as Kuo Shenlin

Hikaru Tono
as Wang Yujia

Karin Takahashi
as Miliam Hildegard von Guropius

Haruna Ishii
as Funada Kiito