Police Chief Jim Fitzpatrick is after gangster Sam Belmonte. He uses his own corrupt brother Ed to watch over Daisy who was associated with Belmonte.

Walter Huston
as Captain James Edward "Jim" Fitzpatrick aka Fighting Fitz

Jean Harlow
as Daisy Stevens aka Mildred Beaumont

Wallace Ford
as Detective Ed Fitzpatrick

Jean Hersholt
as Samuel "Sam" Belmonte

Dorothy Peterson
as Mary Fitzpatrick

Tully Marshall
as Defence Attorney Michaels

Emmett Corrigan
as Chief of Police "Burt" Burton

Warner Richmond
as Detective Tom

Sandy Roth
as Lieutenant John "Mac" Majkowski

J. Carrol Naish
as Pietro Cholo