Eddie is a con artist. When he's framed and comes before a judge, he hopes to get off the hook by climbing insanity—but instead ends up in a hospital for a mental assessment. That night, a storm causes a power failure and, in the ensuing chaos, Eddie is mistaken for a doctor and suddenly finds himself in charge of the hospital.
Richard Pryor
as Eddie Lenahan/Dr. Kevin Slattery
Rachel Ticotin
as Rachel Atwood
Rubén Blades
as Louis
Maria Cardinale
as Herself
Joe Mantegna
as Arthur Chambers
Bob Dishy
as Dr. Foster
Sylvia Miles
as Nurse Maggie Lesser
Joe Dallesandro
as Stucky
Randall "Tex" Cobb
as Box
Bob Saget
as Dr. Joffe