The biography of Dr. W.T. Morgan, a 19th century Boston dentist, during his quest to have anesthesia, in the form of ether, accepted by the public and the medical and dental establishment.

Joel McCrea
as William Thomas Green Morton

Betty Field
as Elizabeth Morton

Harry Carey
as Professor John C. Warren

William Demarest
as Eben Frost

Louis Jean Heydt
as Dr. Horace Wells

Julius Tannen
as Dr. Charles T. Jackson

Edwin Maxwell
as Vice-President of Medical Society

Porter Hall
as President Franklin Pierce

Franklin Pangborn
as Dr. Heywood

Grady Sutton
as Homer Quimby