The construction of the Great Western Railroad creates heavy conflict between the railway company and neighboring Indian tribes. Worse, criminal gang leader Santer sets his eyes on a gold mine located on holy Indian land and influences the construction supervisor to re-rout the planned railroad straight through Apache land. Old Shatterhand, who works as a measurement technician, discovers the evil plan and searches contact with the Apaches in an effort to avert war.

Lex Barker
as Old Shatterhand

Pierre Brice
as Winnetou

Mario Adorf
as Frederic Santer

Marie Versini
as Nscho-tschi

Chris Howland
as Lord Tuff-Tuff

Walter Barnes
as Bill Jones

Ralf Wolter
as Sam Hawkens

Milivoje 'Mavid' Popović
as Intschu-tschuna

Dunja Rajter
as Belle

Nikša Stefanini
as Bullock