Splice

Elsa and Clive, two young rebellious scientists, defy legal and ethical boundaries and forge ahead with a dangerous experiment: splicing together human and animal DNA to create a new organism. Named "Dren", the creature rapidly develops from a deformed female infant into a beautiful but dangerous winged human-chimera, who forges a bond with both of her creators - only to have that bond turn deadly.

Cast

Adrien Brody

as Clive Nicoli

Sarah Polley

as Elsa Kast

Delphine Chanéac

as Dren

Brandon McGibbon

as Gavin Nicoli

Simona Măicănescu

as Joan Chorot

David Hewlett

as William Barlow

Abigail Chu

as Child Dren

Doug Hicton

as Lab tech (uncredited)

Reviews

Andres Gomez

The FX is OK and the uneasiness and thrill is always there but the script is stereotypical, weak and full of holes....

John Chard

Brundledren! Splice is a tricky picture to evaluate, for its ideas are superb. One could argue that it brings a new petri dish full of meddling scientists facing the consequences of their actions, while conversely it justifiably feels like a Cronenberg knock-off. Psychological discord is in ab...

CinemaSerf

"Clive" (Adrien Brody) and "Elsa" (Sarah Polley) are a couple of genetic engineers charged by David Hewlett's "Barlow" with discovering an important gene that could lead to huge advances in medical science. Using a mix of human and animal DNA that have varying degrees of success before the evolution...

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