Jon Lansdale is a comic book artist who loses his right hand in a car accident. The hand was not found at the scene of the accident, but it soon returns by itself to follow Jon around, and murder those who anger him.

Michael Caine
as Jonathan Lansdale

Andrea Marcovicci
as Anne Lansdale

Annie McEnroe
as Stella Roche

Bruce McGill
as Brian Ferguson

Viveca Lindfors
as Psychologist

Rosemary Murphy
as Karen Wagner

Mara Hobel
as Lizzie Lansdale

Pat Corley
as Sheriff

Nicholas Hormann
as Bill Richamn

Edward Marshall
as Doctor (as Ed Marshall)