Reverend Brooks leads his small Iowa town in a contest to stop smoking for a month. But some tobacco executives don't want them to win, and try everything they can to make them smoke. If townspeople don't go nuts from wanting a cigarette, or kill each other from irritation and frustration, they will win a huge prize.

Dick Van Dyke
as Rev. Clayton Brooks

Pippa Scott
as Natalie Brooks

Tom Poston
as Mr. Stopworth

Edward Everett Horton
as Hiram C. Grayson

Bob Elliott
as Hugh Upson / David Chetley / Sandy Van Andy

Vincent Gardenia
as Mayor Wappler

Barnard Hughes
as Dr. Proctor

Graham Jarvis
as Amos Bush

Jean Stapleton
as Mrs. Wappler

Paul Benedict
as Zen Buddhist