Maggie is an alluring free spirit who won't let anyone – or anything – tie her down. But she meets her match in Jamie, whose relentless and nearly infallible charm serves him well with the ladies and the cutthroat world of pharmaceutical sales. Maggie and Jamie's evolving relationship takes them both by surprise, as they find themselves under the influence of the ultimate drug: love.

Jake Gyllenhaal
as Jamie Randall

Anne Hathaway
as Maggie Murdock

Oliver Platt
as Bruce Winston

Hank Azaria
as Dr. Stan Knight

Josh Gad
as Josh Randall

Gabriel Macht
as Trey Hannigan

Judy Greer
as Cindy

Jill Clayburgh
as Nancy Randall

George Segal
as Dr. James Randall

Kate Jennings Grant
as Gina
Nathan
On the surface, Love & Other Drugs appears to be a typical romantic comedy that follows the tried-and-true formula of a ladies' man, Jamie (played by Jake Gyllenhaal), falling in love with his latest hookup, Maggie (played by Anne Hathaway). However, what sets this movie apart from its contemporarie...