In Columbo's first outing, a psychiatrist uses a patient he is having an affair with to help him kill his wife, but his perfect alibi may come apart at the hands of a seemingly befuddled LAPD lieutenant.

Peter Falk
as Columbo

Gene Barry
as Dr. Ray Flemming

Katherine Justice
as Joan Hudson

William Windom
as Burt Gordon

Nina Foch
as Carol Flemming

Virginia Gregg
as Miss Petrie

Andrea King
as Cynthia Gordon

Susanne Benton
as The Blonde

Ena Hartman
as Nurse

Sherry Boucher
as Air Hostess
Wuchak
***“Prescription: Murder” (1968)*** PLOT: An arrogant, nonchalant psychiatrist (Gene Barry) murders his wife and uses his naïve actress girlfriend to get away with it (Katherine Justice), but Lt. Columbo strongly suspects the therapist and steadfastly works to obtain evidence. William Windom is o...
GenerationofSwine
As far as detectives go, Columbo is my guy. He's the wrinkled low expectation mess that uses his appearance and working class persona to lull everyone into a felling of superiority that he can exploit... ... and that really works for the detective genre. Most everything else has more of a gimmick...