James Herriot is a vet in Yorkshire, England, during the 1930s. He is assigned to the practice of Siegfried Farnon, who—together with his mischievous brother Tristan—already have a successful business. James undergoes a variety of adventures during his work, which are just as often caused by the characters of the county, including the Farnon brothers, as the animals in his care.

Simon Ward
as James Herriot

Anthony Hopkins
as Siegfried Farnon

Lisa Harrow
as Helen Alderson

Brian Stirner
as Tristan Farnon

Freddie Jones
as Cranford

T. P. McKenna
as Soames

Brenda Bruce
as Miss Harbottle

John Collin
as Mr Alderson

Christine Buckley
as Mrs Hall

Jane Collins
as Connie