School nurse Alice Goodwin lives with her husband and two daughters on a dairy farm in a small Wisconsin community. After an accident on her property involving a friend's child, the town turns against her and Alice finds herself fighting charges of child abuse.

Sigourney Weaver
as Alice Goodwin

Julianne Moore
as Theresa Collins

David Strathairn
as Howard Goodwin

Arliss Howard
as Paul Reverdy

Chloë Sevigny
as Carole Mackessy

Sara Rue
as Debbie

Aunjanue Ellis-Taylor
as Dyshett

Nicole Ari Parker
as Sherry

Bruklin Harris
as Lynelle

Lisa Emery
as Susan Durkin