Little Opao and Biboy grew up together in an orphanage in Taal, Batangas and promised themselves to be best friends forever. As they grow older they head into separate ways; to be adopted by their respective new parents. Opao is adopted by a spinster whose failed career in acting prompts her to mould Opao into a superstar with the nickname Darling. Meanwhile, Biboy is adopted by Crisp Pops.

Judy Ann Santos
as Opao / Darling

Ogie Alcasid
as Biboy / Frida

Regine Velasquez
as Chit

Roderick Paulate
as Crisp Pop Montojo

Manilyn Reynes
as Monica

Nova Villa
as Sita

John Prats
as Bob

Sharon Cuneta
as Guada

Carmi Martin
as Inday Langging

Jon Avila
as Bambam Baderos