Set against the backdrop of the prescription drug and opioid crisis in the USA, Jamie Sisley depicts the individual consequences of a societal tragedy, while taking an unflinching yet gentle look at a complicated web of relationships.

Wyatt Oleff
as Ethan

Fin Argus
as Derek

Chrissy Metz
as Michelle

Albert Jones
as Dennis

Cree Cicchino
as Melanie

Quinn McColgan
as Ashley

Lorrie Odom
as Vicki

Maxwell Whittington-Cooper
as Mark

Mary Jo Mecca
as Ruby

Rosemary Howard
as Sheriff Lambert