At the age of ten, Henry James Hermin, a boy who was conceived in a petri-dish and raised by his feminist mother, follows a string of Post-It notes in hopes of finding his biological father.

Michael Sheen
as Dr. Slavkin O'Hara

Toni Collette
as Patricia Herman

Jason Spevack
as Henry James Herman

Samantha Weinstein
as Audrey O'Hara

Melyssa Ade
as Kindergarten Teacher

Oprah Winfrey
as Oprah

Frank Moore
as Stan Herman

Paul Braunstein
as Dr. Gunther Flowers

Hannah Brigden
as Young Patricia Herman

Sarah Orenstein
as Mother Herman