Anne and "Poppy" Rose have three quirky kids. Anne has a generous heart and the belief in the innocence of children. To the unhappy surprise of her husband she takes in the orphan Jane, a problem child who already tried to kill herself once.

Cary Grant
as George "Poppy" Rose

Betsy Drake
as Anna Perrott Rose

Lurene Tuttle
as Miss Kenyon

Randy Stuart
as Mrs. Gladys Foreman

John Ridgely
as Harry Foreman

Irving Bacon
as Mayor Michael J. Kane

Mary Treen
as Grace Roberts (as Mary Lou Treen)

Iris Mann
as Jane Miller

George Winslow
as Teenie Rose

Clifford Tatum Jr.
as Jimmy John Wilson